[UPDATED Sep. 2026] This writeup was inspired by talks I gave at the "Bio-IT World 2025" conference in Boston, and at the "Aging & Gerontology 2025" conference in San Francisco. [UPDATE: also, a talk I gave at the 34th conference on "Intelligent Systems for Molecular Biology (ISMB)", in Washington DC, July 2026] An older VIDEO VERSION of this presentation exists (shorter and dating back to Apr. 2025) Life123 is an open-source platform for quantitative interactomics, aiming towards simulations of virtual biological cells or parts thereof – among other things. And it has a slogan: AI and Big Data aren't enough! We also need Dynamical modeling. What does it mean to say "engine for quantitative reactomics"? It means that we perform dynamical modeling of biological systems. And the initial focus is towards eventually creating whole-cell simulations. The platform consists of py...