NOTE: A VIDEO VERSION of this blog entry also exists (slightly outdated to Apr. 2025) [DRAFT IN-PROGRESS] This write-up was inspired by talks I recently gave at the "Bio-IT World 2025" conference in Boston and at the "Aging & Gerontology 2025" conference in San Francisco . Overview Life123 is an open-source platform for quantitative interactomics. Its name is . And it has a slogan – more on this later... The slogan is “AI and Big Data aren't enough! We also need Dynamical modeling.” Let's start with an overview of the Life123 project. It's an open-source engine for quantitative reactomics. But what does it mean? It means that we perform dynamical modeling of biological systems. And the initial focus is towards eventually creating whole-cell simulations. The platform consists of python libraries, which allow us to do in-silico experiments. Early this year, this project left the beta stage, after a few ...